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  <title>UNHINGED with Dr. Michael Meneghini</title>

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  <copyright>© 2026 UNHINGED with Dr. Michael Meneghini</copyright>
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  <itunes:author>Dr. Michael Meneghini</itunes:author>
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  <description><![CDATA[<p>The ground is shifting, but not everyone is saying it out loud.&nbsp;<br><br></p><p>Healthcare is changing. Orthopedics is evolving.</p><p>Leadership is getting harder. Trust matters more than ever.</p><p>Yet, most industry conversations still feel polished, filtered, and safe.</p><p>UNHINGED was built to create the conversations people are actually having behind the scenes — the ones that don't happen on stage.<br><br></p><p>Here, we have real conversations in healthcare and MedTech, said out loud.<br><br>This is a podcast where experienced operators speak honestly about healthcare, business, and leadership in a setting that feels human. This is NOT chaos for the sake of chaos “unhinged.” It’s controlled honesty from credible people.<br><br>Check out new episodes every month. <br>Follow UNHINGED with Dr. Michael Meneghini on YouTube or wherever you get your podcasts.<br><br>LinkedIn: <a href="https://www.youtube.com/redirect?event=video_description&amp;redir_token=QUFFLUhqbXpoYlJVcnVHUHRyV212UzRFbWlmbHNveDhld3xBQ3Jtc0trWDBDeGhiLUx5UEF2c2s0QThfd1FNQ0dJZ3oxbTVrb2U3QmJJMmhoeFpnRlh4dzl3Q3BJZVRLb3phUFhCUkpaSk1xRngwekhoR29odkFuaThaV2ZOaTNrYVE3MkQ0V1Q0VVluRXZtdHF4NkYxZGduSQ&amp;q=https%3A%2F%2Fwww.linkedin.com%2Fin%2Fdr-michael-meneghini-5904854&amp;v=zIKwG-25nZA">/dr-michael-meneghini-5904854&nbsp; </a><br>Substack: substack.com/@michaelmeneghini<br>TikTok: tiktok.com/@drmichaelmeneghini</p>]]></description>
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    <itunes:title>UNHINGED Episode 1, The Silent Killer | Chris Hughes &amp; Eric Stookey of OsteoRemedies </itunes:title>
    <title>UNHINGED Episode 1, The Silent Killer | Chris Hughes &amp; Eric Stookey of OsteoRemedies </title>
    <itunes:summary><![CDATA[Infection after joint replacement is one of the few problems in orthopedics where the stakes can go from “recover and rehab” to “fight for your life” in a matter of weeks. We sit down with Chris Hughes and Eric Stookey, two longtime orthopedics operators who built OsteoRemedies by doing what most companies would not: going all-in on joint infection (PJI) and infection management while everyone else treated it like a side project.  We talk candidly about the entrepreneurship leap in healthcare...]]></itunes:summary>
    <description><![CDATA[<p>Infection after joint replacement is one of the few problems in orthopedics where the stakes can go from “recover and rehab” to “fight for your life” in a matter of weeks. We sit down with Chris Hughes and Eric Stookey, two longtime orthopedics operators who built OsteoRemedies by doing what most companies would not: going all-in on joint infection (PJI) and infection management while everyone else treated it like a side project.<br/><br/>We talk candidly about the entrepreneurship leap in healthcare and medical devices, including the lonely early days of shipping product, assembling conference booths, and learning that a napkin plan only survives through execution. Chris and Eric break down how they protect culture as they scale, why they “check titles at the door,” and how “micro leadership” means removing obstacles so teams can move fast without getting micromanaged. We also get into the messy truth of innovation: FDA and 510(k) hurdles, changing goalposts, multi-year gaps in launches, and why acquisitions can restore the cadence of innovation when organic pathways slow down.<br/><br/>Then we go straight at the market forces shaping orthopedic infection care right now: antibiotic spacers, local antibiotic delivery beads, debridement tools, wash solutions, and the rising debate over one-stage vs two-stage revision. Their core argument is simple: if the standard of care shifts, a patient-first company cannot cling to a single product category. It has to build an infection management portfolio that follows the clinical need.<br/><br/>If you care about PJI, orthopedic infection prevention, medical device startups, or leadership that holds up under pressure, subscribe, share this with a colleague, and leave a review. What part of the infection story do you think the industry still avoids talking about?</p>]]></description>
    <content:encoded><![CDATA[<p>Infection after joint replacement is one of the few problems in orthopedics where the stakes can go from “recover and rehab” to “fight for your life” in a matter of weeks. We sit down with Chris Hughes and Eric Stookey, two longtime orthopedics operators who built OsteoRemedies by doing what most companies would not: going all-in on joint infection (PJI) and infection management while everyone else treated it like a side project.<br/><br/>We talk candidly about the entrepreneurship leap in healthcare and medical devices, including the lonely early days of shipping product, assembling conference booths, and learning that a napkin plan only survives through execution. Chris and Eric break down how they protect culture as they scale, why they “check titles at the door,” and how “micro leadership” means removing obstacles so teams can move fast without getting micromanaged. We also get into the messy truth of innovation: FDA and 510(k) hurdles, changing goalposts, multi-year gaps in launches, and why acquisitions can restore the cadence of innovation when organic pathways slow down.<br/><br/>Then we go straight at the market forces shaping orthopedic infection care right now: antibiotic spacers, local antibiotic delivery beads, debridement tools, wash solutions, and the rising debate over one-stage vs two-stage revision. Their core argument is simple: if the standard of care shifts, a patient-first company cannot cling to a single product category. It has to build an infection management portfolio that follows the clinical need.<br/><br/>If you care about PJI, orthopedic infection prevention, medical device startups, or leadership that holds up under pressure, subscribe, share this with a colleague, and leave a review. What part of the infection story do you think the industry still avoids talking about?</p>]]></content:encoded>
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    <itunes:author>Dr. Michael Meneghini</itunes:author>
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    <pubDate>Mon, 13 Jul 2026 15:00:00 -0400</pubDate>
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  <psc:chapter start="1:20" title="Welcome To Unhinged And Why We Talk" />
  <psc:chapter start="3:19" title="Chris And Eric Origin Stories" />
  <psc:chapter start="6:45" title="Friendship As A Business Advantage" />
  <psc:chapter start="18:23" title="The Entrepreneurship Leap And Early Chaos" />
  <psc:chapter start="25:40" title="Culture First Hiring And Micro Leadership" />
  <psc:chapter start="30:10" title="Betting On The Infection Market" />
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  <psc:chapter start="42:34" title="Beyond Spacers Toward Full Infection Management" />
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