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Polvinen E, Matilainen M, Nylund M, Sucksdorff M, Airas LM. TSPO-Detectable Chronic Active Lesions Predict Disease Progression in Multiple Sclerosis - PMC (nih.gov) Neurol Neuroimmunol Neuroinflamm. 2023 Jun 22;10(5):e200133

Linnerbauer M, Beyer T, Nirschl L, Farrenkopf D, Lößlein L, Vandrey O, Peter A, Tsaktanis T, Kebir H, Laplaud D, Oellinger R, Engleitner T, Alvarez JI, Rad R, Korn T, Hemmer B, Quintana FJ, Rothhammer V. PD-L1 positive astrocytes attenuate inflammatory functions of PD-1 positive microglia in models of autoimmune neuroinflammation - PubMed (nih.gov)Nat Commun. 2023 Sep 9;14(1):5555. doi: 10.1038/s41467-023-40982-8. PMID: 37689786; PMCID: PMC10492803.

 Positron emission tomography with [18 F]-DPA-714 unveils a smoldering component in most multiple sclerosis lesions which drives disease progression - PubMed (nih.gov) Hamzaoui, M., Garcia, J., Boffa, G., Lazzarotto, A., Absinta, M., Ricigliano, V.A.G., Soulier, T., Tonietto, M., Gervais, P., Bissery, A., Louapre, C., Bottlaender, M., Bodini, B. and Stankoff, B. (2023), Ann Neurol.

In vivo characterization of microglia and myelin relation in multiple sclerosis by combined 11C-PBR28 PET and synthetic MRI - PubMed (nih.gov) Barletta VT, Herranz E, Treaba CA, Mehndiratta A, Ouellette R, Granberg T, Klawiter EC, Ionete C, Sloane JA, Mainero C. J Neurol. 2023 Jun;270(6):3091-3102. 

Association of serum neurofilament light with microglial activation in multiple sclerosis - PubMed (nih.gov) Saraste M, Matilainen M, Vuorimaa A, Laaksonen S, Sucksdorff M, Leppert D, Kuhle J, Airas L. J Neurol Neurosurg Psychiatry. 2023 May 2:jnnp-2023-331051. Epub ahead of print.

Katso Aubagion päivitetty valmisteyhteenveto täältä: Aubagio, INN - teriflunomide (europa.eu)

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Ultrastructural Axon-Myelin Unit Alterations in Multiple Sclerosis Correlate with Inflammation - PubMed (nih.gov) 

van den Bosch A, Hümmert S, Steyer A, Ruhwedel T, Hamann J, Smolders J, Nave K-A, Stadelmann C, Kole MHP, Möbius W, Huitinga I. Ann Neurol. 2023 online ahead of print. doi: 10.1002/ana.26585.

Serum Glial Fibrillary Acidic Protein Compared With Neurofilament Light Chain as a Biomarker for Disease Progression in Multiple Sclerosis - PubMed (nih.gov) 

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Proportion and characteristics of secondary progressive multiple sclerosis in five European registries using objective classifiers - PubMed (nih.gov) 

Forsberg L, Spelman T, Klyve P, Manouchehrinia A, Ramanujam R, Mouresan E, Drahota J, Horakova D, Joensen H, Pontieri L, Magyari M, Ellenberger D, Stahmann A, Rodgers J, Witts J, Middleton R, Nicholas R, Bezlyak V, Adlard N, Hach T, Lines C, Vukusic S, Soilu-Hänninen M, van der Walt A, Butzkueven H, Iaffaldano P, Trojano M, Glaser A, Hillert J. Mult Scler J Exp Transl Clin. 2023 Feb 16;9(1):20552173231153557. doi: 10.1177/20552173231153557.

Osteopontin associates with brain TRM-cell transcriptome and compartmentalization in donors with and without multiple sclerosis: iScience
Cheng-Chih Hsiao, Hendrik J. Engelenburg, Aldo Jongejan, Jing Zhu, Baohong Zhang, Michael Mingueneau, Perry D. Moerland, Inge Huitinga, Joost Smolders, Jörg Hamann
Published: December 09, 2022, Cell; iScience

Immunosuppressive biomaterial-based therapeutic vaccine to treat multiple sclerosis via re-establishing immune tolerance - PMC (nih.gov)
Thanh Loc Nguyen, Youngjin Choi, Jihye Im, Hyunsu Shin, Ngoc Man Phan, Min Kyung Kim, Seung Woo Choi, Jaeyun Kim.
Nat Commun. 2022; 13: 7449.

A single-cell analysis framework allows for characterization of CSF leukocytes and their tissue of origin in multiple sclerosis | Science Translational Medicine
Patrick Ostkamp, Marie Deffner, Andreas Schulte-Mecklenbeck, Christian Wünsch, I-Na Lu, Gregory F Wu, Susan Goelz, Philip L De Jager, Tanja Kuhlmann, Catharina C Gross, Luisa Klotz, Gerd Meyer Zu Hörste, Heinz Wiendl, Tilman Schneider-Hohendorf, Nicholas Schwab
Sci Transl Med. 2022 Nov 30;14(673):eadc9778.

Toward Precision Phenotyping of Multiple Sclerosis
David Pitt, Chih Hung Lo, Susan A. Gauthier, Richard A. Hickman, Erin Longbrake, Laura M. Airas, Yang Mao-Draayer, Claire Riley, Philip Lawrence De Jager, Sarah Wesley, Aaron Boster, Ilir Topalli, Francesca Bagnato, Mohammad Mansoor, Olaf Stuve, Ilya Kister, Daniel Pelletier, Panos Stathopoulos, Ranjan Dutta, Matthew R. Lincoln
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